We propose a complete line of reagents from BioDtech, Inc. (BDTI) to develop assays for endotoxin and the ability to remove and neutralize endotoxin
To circumvent these problems, scientists from the National University of Singapore have dissected the enzymatic reaction and identified the molecular site where endotoxin binds to Factor C enzyme which initiates the LAL clotting reaction. The peptide of the sushi domain of the Factor C endotoxin binding site can be made chemically. This is the basis for BDTI's technology for the detection, neutralization and removal of endotoxin.
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